Ed Kilgore has some thoughts on Democratic leadership and the need for term-limits (and specifically for Nancy Pelosi):

Ever since Democrats fell short of their 2016 goal of taking back control of the U.S. House, there’s been talk about […] leadership change in the House Democratic Caucus. And after Democrats failed to win any of the four GOP House seats where special elections were held this year, there was renewed talk about Nancy Pelosi stepping down as House Democratic Leader. The negative buzz became particularly loud after the party’s biggest special-election hope, Georgia’s Jon Ossoff, suffered a disappointing loss, in the wake of Republicans running many millions of dollars of ads linking the candidate to Pelosi.

[…]

[Pelosi] is a much bigger target for Republicans than Paul Ryan or Mitch McConnell appears to be for Democrats. Part of the problem may simply be that she happens to represent a jurisdiction with rich negative symbolism (dating back at least to the attacks on “San Francisco Democrats” in 1984 after the Donkey Party held its convention in the City by the Bay) for the conservatives who are mostly the target for anti-Pelosi ads. You cannot quite imagine Democrats running ads mocking Paul Ryan’s Wisconsin or Mitch McConnell’s Kentucky in this manner.

Emphasis added by me because Kilgore completely discounts the most important information in his several paragraphs. The demonization of Pelosi has nothing to do with her having been in the arena for too long, being a woman, coming from San Francisco, or anything else. Those are all useful pegs for the GOP to build their messaging on and around, but they aren’t themselves decisive or even all that interesting. Anyone serving as minority leader will immediately come under sustained and focused attack from the right wing and their stenographers in much of the media. It’s Cokie’s Law: if information, factual or otherwise, is “out there” then it must be discussed uncritically. Thus the media happily carries the GOP messaging machine’s water on Pelosi and anybody else in the cross-hairs that day. There’s just no getting around it, and The Democrat not only doesn’t have anything like this, they aren’t even on the same planet with the scale and coordination of this operation. Unless and until they create a sustained messaging attack on McConnell and Ryan, those two can continue right on doing what they’re doing. Just to focus on McConnell, he’s likely the most destructive force in government today, but most people would be hard pressed to name him, much less know what he’s been up to and why it is dismantling the way our government has, until recently, functioned.
That’s simply not the case for Pelosi, and that has nothing to do with the fact that she’s from San Francisco and everything to do with a sustained, targeted, and years long messaging attack that salts the Earth and leaves useful framing tools for any GOP hopeful to pick up and use, readymade. Democrats try to build the machine from scratch with every individual election, every cycle. How’s that working out for them?

Lastly, if you like the ACA, thank Nancy Pelosi. Period. That doesn’t mean she gets a pass to serve in party leadership forever, but she did that lift more or less with her own political momentum and within the context of the sustained, entirely negative noise machine and well after perceptions about her in the media were set in stone. Think on that as you try to show her the door.